Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
BOSTROM SUSAN L
   2. Issuer Name and Ticker or Trading Symbol
CISCO SYSTEMS INC [CSCO] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
SR VP, Chief Marketing Officer
(Last)
(First)
(Middle)
170 WEST TASMAN DRIVE		 3. Date of Earliest Transaction (Month/Day/Year)
05/21/2007
(Street)

SAN JOSE, CA 95134		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 05/21/2007   M   6,667 A $ 20.53 108,100 D  
Common Stock 05/21/2007   M   16,667 A $ 16.15 124,767 D  
Common Stock 05/21/2007   M   20,000 A $ 9.749 144,767 D  
Common Stock 05/21/2007   M   20,000 A $ 13.04 164,767 D  
Common Stock 05/21/2007   M   40,000 A $ 19.59 204,767 D  
Common Stock 05/21/2007   M   45,000 A $ 19.18 249,767 D  
Common Stock 05/21/2007   M   30,000 A $ 17.86 279,767 D  
Common Stock 05/21/2007   M   62,500 A $ 19.4 342,267 D  
Common Stock 05/21/2007   S   18,819 D $ 26.47 323,448 D  
Common Stock 05/21/2007   S   73,409 D $ 26.46 250,039 D  
Common Stock 05/21/2007   S   148,606 D $ 26.45 101,433 D  
Common Stock               999 I by Trust (1)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Non-Qualified Stock Option (right to buy) $ 20.53 05/21/2007   M     6,667 01/07/2003(2) 01/07/2011 Common Stock 6,667 $ 0 0 D  
Non-Qualified Stock Option (right to buy) $ 16.15 05/21/2007   M     16,667 04/05/2003(2) 04/05/2011 Common Stock 16,667 $ 0 0 D  
Non-Qualified Stock Option (right to buy) $ 9.749 05/21/2007   M     20,000 10/10/2003(2) 10/10/2011 Common Stock 20,000 $ 0 16,667 D  
Non-Qualified Stock Option (right to buy) $ 13.04 05/21/2007   M     20,000 04/10/2004(2) 04/10/2012 Common Stock 20,000 $ 0 36,667 D  
Non-Qualified Stock Option (right to buy) $ 19.59 05/21/2007   M     40,000 09/02/2004(2) 09/02/2012 Common Stock 40,000 $ 0 106,667 D  
Non-Qualified Stock Option (right to buy) $ 19.18 05/21/2007   M     45,000 08/23/2005(2) 08/23/2013 Common Stock 45,000 $ 0 210,000 D  
Non-Qualified Stock Option (right to buy) $ 17.86 05/21/2007   M     30,000 09/29/2006(2) 09/29/2014 Common Stock 30,000 $ 0 205,000 D  
Non-Qualified Stock Option (right to buy) $ 19.4 05/21/2007   M     62,500 02/08/2007(2) 02/08/2015 Common Stock 62,500 $ 0 187,500 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
BOSTROM SUSAN L
170 WEST TASMAN DRIVE
SAN JOSE, CA 95134		       SR VP, Chief Marketing Officer  

Signatures

 /s/ Susan L. Bostrom, by Evan Sloves, Attorney-in-fact   05/23/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Bostrom Family Trust.
(2) The option vests as to twenty percent (20%) of the shares on the one (1) year anniversary of the grant date, and as to the remaining eighty percent (80%) of the shares thereafter in forty eight (48) successive equal monthly installments.

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