UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                   ----------

                                    FORM 8-K

                                 CURRENT REPORT
                     PURSUANT TO SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

                DATE OF REPORT (DATE OF EARLIEST EVENT REPORTED):

                                 October 2, 2008

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                                 XENOMICS, INC.
             (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)

                                     FLORIDA
                 (STATE OR OTHER JURISDICTION OF INCORPORATION)

       333-103083                                      04-3721895
(COMMISSION FILE NUMBER)                  (I.R.S. EMPLOYER IDENTIFICATION NO.)


                          One Deer Park Drive, Suite F
                           Monmouth Junction, NJ 08852
                    (ADDRESS OF PRINCIPAL EXECUTIVE OFFICES)

                                 (732) 438-8290
              (REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE)

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

[  ] Written communications  pursuant to Rule 425 under the Securities Act (17
     CFR 230.425)

[  ] Soliciting  material  pursuant to Rule 14a-12 under the Exchange Act (17
     CFR 240.14a-12)

[  ] Pre-commencement  communications  pursuant  to Rule  14d-2(b)  under the
     Exchange Act (17 CFR 240.14d-2(b))

[  ] Pre-commencement  communications  pursuant  to Rule  13e-4(c)  under the
     Exchange Act (17 CFR 240.13e-4(c))



ITEM 1.01    ENTRY INTO A MATERIAL DEFINITIVE AGREEMENT.

At a meeting of the Board of Directors (the "Board") of the Company held on
October 2, 2008, the Board advised Dr. Gianluigi Longinotti-Buitoni, the
Company's Chairman, that it will exercise its put option, to the maximum amount,
under the Warrant and Put Option Agreement, originally dated as of November 30,
2006, as amended (the "Agreement"), between the Company and Dr.
Longinotti-Buitoni. Under the Agreement, the Company is requiring Dr.
Longinotti-Buitoni to invest up to $1,000,000 in the Company for the purchase of
up to 1,818,181 units, each unit consisting of one share of the Company's common
stock and one warrant, at a purchase price of $0.55 per unit. Each warrant is
exercisable to purchase one share of the Company's common stock at a price of
$0.70 per share and expires in November 2012. The purchase of the units by Dr.
Longinotti-Buitoni under the terms of the Agreement is not assured as Dr.
Longinotti-Buitoni has indicated that he will reply to the Company's put notice
by the end of this week.

ITEM 5.02    DEPARTURE OF DIRECTORS OR PRINCIPAL OFFICERS; ELECTION OF
DIRECTORS; APPOINTMENT OF PRINCIPAL OFFICERS; COMPENSATORY ARRANGEMENTS OF
CERTAIN OFFICERS.

At the same Board meeting, Dr. Longinotti-Buitoni and the Board agreed that,
effective October 3, 2008, Dr. Longinotti-Buitoni would no longer serve in an
executive capacity as the Company's Executive Chairman. He will continue to
serve as Chairman of the Company's Board of Directors. The Board established an
Executive Committee to be chaired by Dr. Kira Sheinerman and constituted with
Dr. David Sidransky. It is anticipated that the Executive Committee will meet
more frequently than the Board and will act on behalf of the Board between Board
meetings to actively exercise oversight responsibility over management and the
business and affairs of the Company, and closely monitor the execution of the
Company's business plan as defined by the Board. The Committee will focus on
management's bringing the Company into an opportune business position and
securing long term funding to carry out the company's business plan as it begins
to commercialize its technology. At the same time, the Executive Committee will
institute a search for a seasoned Chief Executive Officer with experience
relevant to the development and marketing of diagnostic products and tests.

ITEM 8       OTHER EVENTS

At the current time, the Company's financial resources are low and the Company
has made a decision to reduce certain laboratory operations. If new capital is
not brought into the Company in the near future, the Company's ability to
continue as a going concern will be in question. The Company intends to actively
work towards improving its financial position and will consider available
options to resolve the deficiency and regain the full operational status.

FORWARD LOOKING STATEMENTS

Some of the statements in this Form 8-K constitute "forward-looking statements"
within the meaning of the United States Private Securities Litigation Reform Act
of 1995. These statements are based on our current expectations, estimates and
projections. Words such as "will," "expects," "believes" and similar expressions
are used to identify these forward-looking statements. The forward-looking
statements in this Form 8-K include, without limitation, the purchase of units
by Dr. Longinotti-Buitoni and potential consequences. These statements are only
predictions and as such are not guarantees of future performance and involve
risks, uncertainties and assumptions that are difficult to predict.
Forward-looking statements are based upon assumptions as to future events or our
future financial performance that may not prove to be accurate. Actual outcomes
and results may differ materially from what is expressed or forecast in these
forward-looking statements, including an adverse court determination, changes in
law, rules or regulations and other actions of parties adverse to the Company in
regard to its rights under its outstanding debt obligations. As a result, these
statements speak only as of the date they were made, and the Company undertakes
no obligation to publicly update or revise any forward-looking statements,
whether as a result of new information, future events or otherwise.



                                    SIGNATURE

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                     XENOMICS, INC.

Date: October 8, 2008                By: /s/Gary Anthony
                                         ---------------------------------------
                                     Gary Anthony, Vice President and Controller