1. Title of Derivative Security (Instr. 4) |
2. Date Exercisable and Expiration Date (Month/Day/Year) |
3. Title and Amount of Securities Underlying Derivative Security (Instr. 4) |
4. Conversion or Exercise Price of Derivative Security |
5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5) |
6. Nature of Indirect Beneficial Ownership (Instr. 5) |
Date Exercisable |
Expiration Date |
Title |
Amount or Number of Shares |
Series B Preferred Stock
|
Â
(1)
|
Â
(1)
|
Common Stock
|
681,260
|
$
(1)
|
I
|
See Footnote
(7)
|
Series D Preferred Stock
|
Â
(2)
|
Â
(2)
|
Common Stock
|
34,186
|
$
(2)
|
I
|
See Footnote
(7)
|
Series E-1 Preferred Stock
|
Â
(3)
|
Â
(3)
|
Common Stock
|
97,796
|
$
(3)
|
I
|
See Footnote
(7)
|
Series F Preferred Stock
|
Â
(4)
|
Â
(4)
|
Common Stock
|
178,414
|
$
(4)
|
I
|
See Footnote
(7)
|
Series E Preferred Stock
|
Â
(5)
|
Â
(5)
|
Common Stock
|
92,471
|
$
(5)
|
I
|
See Footnote
(7)
|
Common Stock Purchase Warrant (Right to Buy)
|
05/24/2011 |
05/24/2021 |
Common Stock
|
15,053
(6)
|
$
1.55
|
I
|
See Footnote
(7)
|
* |
If the form is filed by more than one reporting person, see Instruction 5(b)(v). |
** |
Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). |
(1) |
The Series B Preferred Stock is convertible into Common Stock on a 11.009-for-one basis into the number of shares of Common Stock shown in Column 3 at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares have no expiration date. |
(2) |
The Series D Preferred Stock is convertible into Common Stock on a 11.009-for-one basis into the number of shares of Common Stock shown in Column 3 at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares have no expiration date. |
(3) |
The Series E-1 Preferred Stock is convertible into Common Stock on a 11.009-for-one basis into the number of shares of Common Stock shown in Column 3 at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares have no expiration date. |
(4) |
The Series F Preferred Stock is convertible into Common Stock on a 11.009-for-one basis into the number of shares of Common Stock shown in Column 3 at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares have no expiration date. |
(5) |
The Series E Preferred Stock is convertible into Common Stock on an 8.56256-for-one basis into the number of shares of Common Stock shown in Column 3 at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares have no expiration date. |
(6) |
The warrant is currently exercisable, with an expiration date of May 24, 2021, and an exercise price of $1.55 per share. The exercise price may be paid in cash or through net share settlement at the option of the warrantholder. |
(7) |
The shares reported herein are held of record by S.R. One, Limited, an indirect, wholly-owned subsidiary of GlaxoSmithKline plc (the "Reporting Person"). |