Shares of Common | Shares of Common | |||||||||||||||||||
Stock Beneficially | Number | Stock Beneficially | ||||||||||||||||||
Owned Prior to the | of | Owned After | ||||||||||||||||||
Offering | Shares | Offering | ||||||||||||||||||
Being | ||||||||||||||||||||
Security Holders*** | Shares | Percent* | Offered | Shares | Percent* | |||||||||||||||
Oxford BioScience Partners IV L.P. (1), (2) |
1,035,610 | 3.44 | % | 490,819 | 544,791 | 1.81 | % | |||||||||||||
mRNA Fund II L.P. (1), (3) |
10,388 | * | * | 5,104 | 5,284 | * | * | |||||||||||||
125 Broad Street Fund, LLC |
6,534 | * | * | 6,534 | 0 | * | * | |||||||||||||
AGF IART |
13,069 | * | * | 13,069 | 0 | * | * | |||||||||||||
AGF VIE |
30,494 | * | * | 30,494 | 0 | * | * | |||||||||||||
Akzo Nobel Pharma Ventures B.V. |
4,356 | * | * | 4,356 | 0 | * | * | |||||||||||||
Alexandra R. Pearsall |
26 | * | * | 26 | 0 | * | * | |||||||||||||
Alison Taunton-Rigby |
218 | * | * | 218 | 0 | * | * | |||||||||||||
ALPHA 2001 L.P. |
10,891 | * | * | 10,891 | 0 | * | * | |||||||||||||
American Family Mutual Insurance Company |
30,494 | * | * | 30,494 | 0 | * | * | |||||||||||||
Artal Invest Ltd. |
43,563 | * | * | 43,563 | 0 | * | * | |||||||||||||
Ashley J. Stevens |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Barry I. Eisenstein |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Bear Stearns Private Equity Limited |
10,891 | * | * | 10,891 | 0 | * | * | |||||||||||||
Bernd R. Seizinger |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Big Woods II LLC |
21,781 | * | * | 21,781 | 0 | * | * | |||||||||||||
Brent B. Milner |
218 | * | * | 218 | 0 | * | * | |||||||||||||
California Emerging Ventures II LLC |
130,689 | * | * | 130,689 | 0 | * | * | |||||||||||||
Catherine M. Stone Rev Tr dtd 10/18/99 |
1,089 | * | * | 1,089 | 0 | * | * | |||||||||||||
Chaos Partners I, L.P. |
4,356 | * | * | 4,356 | 0 | * | * | |||||||||||||
Charles Schwab & Co., FBO Richard S.
Foemmel IRA Account |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Christopher Covington |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Cornelius T. Ryan |
108 | * | * | 108 | 0 | * | * | |||||||||||||
Credit Suisse Anlagestiftung |
6,534 | * | * | 6,534 | 0 | * | * | |||||||||||||
CTTV Investments LLC |
8,713 | * | * | 8,713 | 0 | * | * | |||||||||||||
David J. Livingston, Trustee of the David
J. Livingston Rev Trust 2002 |
218 | * | * | 218 | 0 | * | * | |||||||||||||
Dennis H. and Susan F. Langer |
218 | * | * | 218 | 0 | * | * | |||||||||||||
Dogwood Investments, Inc. |
21,781 | * | * | 21,781 | 0 | * | * |
Shares of Common | Shares of Common | |||||||||||||||||||
Stock Beneficially | Number | Stock Beneficially | ||||||||||||||||||
Owned Prior to the | of | Owned After | ||||||||||||||||||
Offering | Shares | Offering | ||||||||||||||||||
Being | ||||||||||||||||||||
Security Holders*** | Shares | Percent* | Offered | Shares | Percent* | |||||||||||||||
Donald E. and Janet L. Schoeny |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Dr. Jules and Mrs. Barbara Blake |
108 | * | * | 108 | 0 | * | * | |||||||||||||
Dr. Stephen Ashley Lawton & Mrs. Alison
Frances Lawton |
218 | * | * | 218 | 0 | * | * | |||||||||||||
Edward B. Roberts |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Edward R. Gates |
326 | * | * | 326 | 0 | * | * | |||||||||||||
Eric W. Roberts |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Fire and Police Pension Association of
Colorado |
21,781 | * | * | 21,781 | 0 | * | * | |||||||||||||
Fort Washington Private Equity Investors
III, L.P. |
43,563 | * | * | 43,563 | 0 | * | * | |||||||||||||
Frederick Frank |
218 | * | * | 218 | 0 | * | * | |||||||||||||
GE Capital Equity Holdings, Inc. |
65,344 | * | * | 65,344 | 0 | * | * | |||||||||||||
General Practitioner LLC |
2,396 | * | * | 2,396 | 0 | * | * | |||||||||||||
Genzyme Corporation |
21,781 | * | * | 21,781 | 0 | * | * | |||||||||||||
Georges Haas |
218 | * | * | 218 | 0 | * | * | |||||||||||||
GIMV NV London Branch |
52,276 | * | * | 52,276 | 0 | * | * | |||||||||||||
Godfrey S. Rockefeller C Tr dtd 12/12/63
FBO Marion R. Stone |
1,089 | * | * | 1,089 | 0 | * | * | |||||||||||||
Gordon M. Binder and Adele H. Binder,
trustees of the Binder Trust dated July
15, 2003 |
13,069 | * | * | 13,069 | 0 | * | * | |||||||||||||
GS PEP 1999 Manager Fund Technology
Holdings, LLC |
1,551 | * | * | 1,551 | 0 | * | * | |||||||||||||
GS PEP Technology Fund 2000 Offshore
Holdings, L.P. |
19,277 | * | * | 19,277 | 0 | * | * | |||||||||||||
GS PEP Technology Fund 2000, L.P. |
48,847 | * | * | 48,847 | 0 | * | * | |||||||||||||
GS Private
Equity Partners 2000 Manager
Fund, L.P. |
18,993 | * | * | 18,993 | 0 | * | * | |||||||||||||
GS Private Equity Partners 2000 Offshore
Holdings, L.P. |
17,207 | * | * | 17,207 | 0 | * | * | |||||||||||||
GS Private Equity Partners 2000, L.P. |
50,925 | * | * | 50,925 | 0 | * | * | |||||||||||||
HarbourVest Partners VI-Parallel
Partnership Fund L.P. |
3,267 | * | * | 40,296 | 0 | * | * | |||||||||||||
HarbourVest Partners VI-Partnership Fund
L.P. |
40,296 | * | * | 3,267 | 0 | * | * | |||||||||||||
HarbourVest VII Venture Ltd. |
21,781 | * | * | 21,781 | 0 | * | * | |||||||||||||
Health Advances, Inc. |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Helen S. Fitzgerald |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Henry E. Blair |
218 | * | * | 218 | 0 | * | * | |||||||||||||
HFI Private Equity, Ltd. |
32,672 | * | * | 32,672 | 0 | * | * | |||||||||||||
Hiorts Finance SA |
8,713 | * | * | 8,713 | 0 | * | * |
Shares of Common | Shares of Common | |||||||||||||||||||
Stock Beneficially | Number | Stock Beneficially | ||||||||||||||||||
Owned Prior to the | of | Owned After | ||||||||||||||||||
Offering | Shares | Offering | ||||||||||||||||||
Being | ||||||||||||||||||||
Security Holders*** | Shares | Percent* | Offered | Shares | Percent* | |||||||||||||||
Howard Hughes Medical Institute |
87,127 | * | * | 87,127 | 0 | * | * | |||||||||||||
Immunex Corporation |
8,713 | * | * | 8,713 | 0 | * | * | |||||||||||||
International Business Machines Corporation |
21,781 | * | * | 21,781 | 0 | * | * | |||||||||||||
Jack H. Morgan |
218 | * | * | 218 | 0 | * | * | |||||||||||||
Jean Montagu |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Jeffrey A. Leerink |
326 | * | * | 326 | 0 | * | * | |||||||||||||
Jeffrey Matthews |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Jennifer P. Stone 1991 Revocable Trust |
1,089 | * | * | 1,089 | 0 | * | * | |||||||||||||
Joel S. Marcus |
436 | * | * | 436 | 0 | * | * | |||||||||||||
John J. & Wendy G. J. Troy |
436 | * | * | 436 | 0 | * | * | |||||||||||||
John R. Brown |
326 | * | * | 326 | 0 | * | * | |||||||||||||
Joseph R. Hyde, III |
43,563 | * | * | 43,563 | 0 | * | * | |||||||||||||
JP Morgan Bank, trustee for the BP Master
Trust for Employee Pension Plans |
43,563 | * | * | 43,563 | 0 | * | * | |||||||||||||
JPMorgan Chase Retirement Plan |
21,781 | * | * | 21,781 | 0 | * | * | |||||||||||||
Justin P. Morreale |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Karl H. Proppe |
218 | * | * | 218 | 0 | * | * | |||||||||||||
Kenneth A. Sorensen |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Kenneth Ward |
218 | * | * | 218 | 0 | * | * | |||||||||||||
Klee USA Fund I, L.P. |
32,672 | * | * | 32,672 | 0 | * | * | |||||||||||||
Larry Abrams |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Lee Brettman |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Los Angeles County Employees Retirement
Association |
87,127 | * | * | 87,127 | 0 | * | * | |||||||||||||
Lucy S. Moore |
1,089 | * | * | 1,089 | 0 | * | * | |||||||||||||
Luna PCC Limited 2000 Cell |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Marc Kozin |
326 | * | * | 326 | 0 | * | * | |||||||||||||
Margraf Investments, LLC |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Marion R. Stone |
1,089 | * | * | 1,089 | 0 | * | * | |||||||||||||
Marion R. Stone Tr dtd 12/30/87 |
2,178 | * | * | 2,178 | 0 | * | * | |||||||||||||
Markaz Offshore Direct Investments |
4,356 | * | * | 4,356 | 0 | * | * | |||||||||||||
Matthew L. Clark |
108 | * | * | 108 | 0 | * | * | |||||||||||||
MC Life Science Ventures, Inc. |
13,069 | * | * | 13,069 | 0 | * | * | |||||||||||||
MCC-PCG International Private Equity Fund |
13,069 | * | * | 13,069 | 0 | * | * | |||||||||||||
Mellon Trust of New England, N.A., f/k/a
Boston Safe Deposit and Trust Company as
Trustee for the Qwest Occupational Health
Trust |
9,802 | * | * | 9,802 | 0 | * | * | |||||||||||||
Mellon Trust of New England, N.A., f/k/a
Boston Safe Deposit and Trust Company as
Trustee for the Qwest Pension Trust |
55,543 | * | * | 55,543 | 0 | * | * |
Shares of Common | Shares of Common | |||||||||||||||||||
Stock Beneficially | Number | Stock Beneficially | ||||||||||||||||||
Owned Prior to the | of | Owned After | ||||||||||||||||||
Offering | Shares | Offering | ||||||||||||||||||
Being | ||||||||||||||||||||
Security Holders*** | Shares | Percent* | Offered | Shares | Percent* | |||||||||||||||
Mellon Trust of New England, N.A., f/k/a
Boston Safe Deposit and Trust Company, as
Trustee for the Raytheon Master Pension
Trust |
87,127 | * | * | 87,127 | 0 | * | * | |||||||||||||
Michael E. Lytton |
53 | * | * | 53 | 0 | * | * | |||||||||||||
Michael R. Pavia |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Nationwide Mutual Insurance Company |
21,781 | * | * | 21,781 | 0 | * | * | |||||||||||||
Nippon Life Insurance Company |
43,563 | * | * | 43,563 | 0 | * | * | |||||||||||||
Nordea Thematic Fund of Funds I k/s |
8,713 | * | * | 8,713 | 0 | * | * | |||||||||||||
OBP Management IV L.P. (1), (4) |
19,998 | * | * | 19,998 | 0 | * | * | |||||||||||||
Palladian Partners 2001, LLC |
10,891 | * | * | 10,891 | 0 | * | * | |||||||||||||
Palmer & Dodge LLP |
218 | * | * | 218 | 0 | * | * | |||||||||||||
Partners Group Private Equity Performance
Holding Limited |
17,425 | * | * | 17,425 | 0 | * | * | |||||||||||||
Paul A. Kirkconnell |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Pearl Holding Limited |
21,781 | * | * | 21,781 | 0 | * | * | |||||||||||||
Peter Lanciano |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Peter O. Kliem & Ann Wolff |
218 | * | * | 218 | 0 | * | * | |||||||||||||
Peter Preuss |
2,178 | * | * | 2,178 | 0 | * | * | |||||||||||||
Peter Wirth |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Philip J. Edmundson |
326 | * | * | 326 | 0 | * | * | |||||||||||||
Philip V. Holberton |
218 | * | * | 218 | 0 | * | * | |||||||||||||
Pravin R. Chaturvedi |
326 | * | * | 326 | 0 | * | * | |||||||||||||
Private Equity Investment Fund IV, LP |
13,069 | * | * | 13,069 | 0 | * | * | |||||||||||||
Private Equity Technology Partners III C.V. |
43,563 | * | * | 43,563 | 0 | * | * | |||||||||||||
Raymond N. Charest |
26 | * | * | 26 | 0 | * | * | |||||||||||||
RGIP, LLC |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Rho Fund Investors II LLC |
21,781 | * | * | 21,781 | 0 | * | * | |||||||||||||
Richard H. Egdahl |
218 | * | * | 218 | 0 | * | * | |||||||||||||
Robert E. Flaherty |
218 | * | * | 218 | 0 | * | * | |||||||||||||
Robert Granovsky |
218 | * | * | 218 | 0 | * | * | |||||||||||||
Robert J. Hennessey |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Scott M. Rocklage |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Shalon Ventures L.P. |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Silicon Valley Bancshares |
2,178 | * | * | 2,178 | 0 | * | * | |||||||||||||
Stone Street PEP Technology Fund 2000, L.P. |
17,451 | * | * | 17,451 | 0 | * | * | |||||||||||||
Suzanne Troy Cole |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Teachers Insurance and Annuity Association
of America |
87,127 | * | * | 87,127 | 0 | * | * | |||||||||||||
TH&T Partners 2001, LLC |
436 | * | * | 436 | 0 | * | * | |||||||||||||
The Bear Stearns Companies, Inc. |
10,891 | * | * | 10,891 | 0 | * | * |
Shares of Common | Shares of Common | |||||||||||||||||||
Stock Beneficially | Number | Stock Beneficially | ||||||||||||||||||
Owned Prior to the | of | Owned After | ||||||||||||||||||
Offering | Shares | Offering | ||||||||||||||||||
Being | ||||||||||||||||||||
Security Holders*** | Shares | Percent* | Offered | Shares | Percent* | |||||||||||||||
The John T. Lupton Trust |
10,891 | * | * | 10,891 | 0 | * | * | |||||||||||||
The Lloyd Cotsen 1985 Trust |
10,891 | * | * | 10,891 | 0 | * | * | |||||||||||||
The Markaz/Hamilton Lane Technology Fund
L.P. |
13,069 | * | * | 13,069 | 0 | * | * | |||||||||||||
The Norinchukin Bank |
21,781 | * | * | 21,781 | 0 | * | * | |||||||||||||
The Regents of the University of California |
108,907 | * | * | 108,907 | 0 | * | * | |||||||||||||
The Robert and Francine Lent Living Trust |
10,891 | * | * | 10,891 | 0 | * | * | |||||||||||||
Timothy B. Stone 1994 Rev Tr |
436 | * | * | 436 | 0 | * | * | |||||||||||||
Timothy R. Surgenor |
218 | * | * | 218 | 0 | * | * | |||||||||||||
Tri-State Growth Capital Fund I L.P. |
21,781 | * | * | 21,781 | 0 | * | * | |||||||||||||
Trustees of Boston University |
8,713 | * | * | 8,713 | 0 | * | * | |||||||||||||
United of Omaha Life Insurance Company |
21,781 | * | * | 21,781 | 0 | * | * | |||||||||||||
Victor W. Schmitt |
326 | * | * | 326 | 0 | * | * | |||||||||||||
Vincent P. Stanton, Jr. |
173 | * | * | 173 | 0 | * | * | |||||||||||||
V-Sciences Fund Investments Pte Ltd |
21,781 | * | * | 21,781 | 0 | * | * | |||||||||||||
Wachovia Investors, Inc. |
21,781 | * | * | 21,781 | 0 | * | * | |||||||||||||
William A. Holodnak |
218 | * | * | 218 | 0 | * | * | |||||||||||||
Subtotal |
3,045,998 | 10.54 | % | 2,495,923 | 550,075 | 1.83 | % | |||||||||||||
* | Percentage calculations based on 30,097,987 shares of our common stock that were issued and outstanding as of January 18, 2006. | |
** | Represents beneficial ownership of less than 1%. | |
*** | Addresses that are not listed are c/o Oxford BioScience Partners VI L.P., 222 Berkeley Street, Boston, MA 02116. | |
(1) | OBP Management IV L.P. is the general partner for Oxford Bioscience Partners IV L.P. and mRNA Fund II L.P. Mark Carthy, a former director of Solexa, is a General Partner of OBP Management IV L.P. and may be deemed to share voting and investment power over the shares held by Oxford Bioscience Partners IV L.P. and mRNA Fund II L.P. Mr. Carthy disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein. Doug Fambrough, a director of Solexa, is affiliated with Oxford Bioscience Partners IV, L.P. and mRNA Fund II L.P. and does not possess voting and/or investment power of the shares held by these entities. Dr. Fambrough disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein. Excludes 1,559 shares of restricted common stock and options to purchase 20,000 shares of common stock held by Dr. Fambrough. | |
(2) | Includes 272,268 shares of common stock issuable upon exercise of a warrant. | |
(3) | Includes 2,732 shares of common stock issuable upon exercise of a warrant. | |
(4) | Excludes 763,342 shares of common stock held by Oxford BioScience Partners IV L.P., 272,268 shares of common stock issuable upon exercise of a warrant held by Oxford BioScience Partners IV L.P., 27,523 shares of common stock held by mRNA Fund II L.P. and 2,732 shares of common stock issuable upon exercise of a warrants held by mRNA Fund II L.P. |