UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549
                         ------------------------------

                                    FORM 8-K

                                 CURRENT REPORT
                       Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934

         Date of report (Date of earliest event reported): June 27, 2006

                             ORION HEALTHCORP, INC.
             (Exact Name of Registrant as Specified in its Charter)

      Delaware                     001-16587                    58-1597246
  (State or Other               (Commission File             (I.R.S. Employer
  Jurisdiction of                     Number)                 Identification
   Incorporation)                                                 Number)

                        1805 Old Alabama Road, Suite 350
                                Roswell, GA 30076
               (Address of Principal Executive Offices) (Zip Code)

                                 (678) 832-1800
              (Registrant's Telephone Number, Including Area Code)

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

     |_|  Written communications pursuant to Rule 425 under the Securities Act
          (17 CFR 230.425)

     |_|  Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17
          CFR 240.14a-12)

     |_|  Pre-commencement communications pursuant to Rule 14d-2(b) under the
          Exchange Act (17 CFR 240.14d-2(b))

     |_|  Pre-commencement communications pursuant to Rule 13e-4(c) under the
          Exchange Act (17 CFR 240.13e-4(c))





Section 4   Matters Related to Accountants and Financial Statements

Item 4.01       Changes in Registrant's Certifying Accountant

     (a)  On June 1, 2006, the partners of UHY Mann Frankfort Stein & Lipp CPAs,
          LLP ("UMFSL") announced that they were joining UHY LLP ("UHY"), a New
          York limited liability partnership. UHY is the independent registered
          public accounting firm with which UMFSL has an affiliation. UHY is a
          legal entity that is separate from UMFSL. On June 27, 2006, UMFSL
          notified Orion HealthCorp, Inc. (the "Company") that it has ceased to
          provide audit services to the Company, and accordingly, resigned as
          the independent public auditors of the Company on that date.

          None of the reports of UMFSL on the Company's financial statements for
          either of the past two years or subsequent interim periods contained
          an adverse opinion or disclaimer of opinion, or was qualified or
          modified as to uncertainty, audit scope or accounting principles,
          except for a going concern opinion expressing substantial doubt about
          the Company's ability to continue as a going concern.

          During the two most recent fiscal years of the Company and any
          subsequent interim periods, there were no disagreements between the
          Company and UMFSL on any matter of accounting principles or practices,
          financial statement disclosure, or auditing scope or procedure, which
          disagreements, if not resolved to the satisfaction of UMFSL, would
          have caused it to make reference to the subject matter of the
          disagreements in connection with its report.

          The Company has provided UMFSL with a copy of the foregoing
          disclosures in conjunction with the filing of this Form 8-K. The
          Company requested that UMFSL deliver to the Company a letter addressed
          to the Securities and Exchange Commission stating whether it agrees
          with the statements made by the Company in response to Item 304(a) of
          Regulation S-B, and if not, stating the respects in which it does not
          agree. A copy of the letter from UMFSL is filed as Exhibit 16.1 to
          this current report.

     (b)  On June 27, 2006, the Company engaged UHY as the Company's independent
          public auditor for the Company's fiscal year ending December 31, 2006
          and the interim periods prior to such year-end. During the Company's
          two most recent fiscal years or subsequent interim period, the Company
          has not consulted with UHY regarding the application of accounting
          principles to a specific transaction, either completed or proposed, or
          the type of audit opinion that might be rendered on the Company's
          financial statements, nor did the limited liability partnership of UHY
          provide advice to the Company, either written or oral, that was an
          important factor considered by the Company in reaching a decision as
          to the accounting, auditing or financial reporting issue. Further,
          during the Company's two most recent fiscal years or subsequent
          interim periods, the Company has not consulted with the limited
          liability partnership of UHY on any matter that was the subject of a
          disagreement or a reportable event.

          The decision to change principal accountants was approved by the Audit
          Committee of the Company's Board of Directors.


Section 9   Financial Statements and Exhibits

Item 9.01       Financial Statements and Exhibits

(d) Exhibits - The following exhibits are furnished as part of this current
report:

Exhibit     Description
-------     -----------
16.1        Letter, dated as of June 30, 2006, from UHY Mann Frankfort Stein &
            Lipp CPAs, LLP to the Securities and Exchange Commission





                                   SIGNATURES


     Pursuant to the requirements of the Securities Exchange Act of 1934, the
Company has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                            ORION HEALTHCORP, INC.


                                            By:   /s/ Stephen H. Murdock
                                                  ------------------------------
                                                      Stephen H. Murdock
                                                      Chief Financial Officer


Date:    June 30, 2006





                                  EXHIBIT INDEX

Exhibit
Number      Description of Exhibits
------      -----------------------

16.1        Letter, dated as of June 30, 2006, from UHY Mann Frankfort Stein &
            Lipp CPAs, LLP to the Securities and Exchange Commission