SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549

                                   FORM 12b-25

                         Commission File Number 0-27282


                           NOTIFICATION OF LATE FILING


(Check One):   [x] Form 10-K and Form 10-KSB   [ ] Form 11-K    [ ] Form 20-F
               [ ] Form 10-Q  [ ] Form N-SAR

          For Period Ended:   December 31, 2002

     [ ]  Transition Report on Form 10-K
     [ ]  Transition Report on Form 20-F
     [ ]  Transition Report on Form 11-K
     [ ]  Transition Report on Form 10-Q
     [ ]  Transition Report on Form N-SAR

          For the Transition Period Ended:
                                          --------------------------------------

     Read attached instruction sheet before preparing form. Please print or
type.

     Nothing in this form shall be construed to imply that the Commission has
verified any information contained herein.

     If the notification relates to a portion of the filing checked above,
identify the item(s) to which the notification relates:
                                                       -------------------------

                                     PART I
                             REGISTRANT INFORMATION

Full name of registrant:  MANHATTAN PHARMACEUTICALS, INC.

Former name if applicable: Atlantic Technology Ventures, Inc.

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Address of principal executive office (Street and number)

787 Seventh Avenue, 48th Floor

City, state and zip code

New York, New York 10019







                                     PART II
                             RULE 12b-25(b) AND (c)

     If the subject report could not be filed without unreasonable effort or
expense and the registrant seeks relief pursuant to Rule 12b-25(b), the
following should be completed. (Check box if appropriate.)

     (a) The reasons described in reasonable detail in Part III of this form
         could not be eliminated without unreasonable effort or expense;

     (b) The subject annual report, semi-annual report, transition report on
         Form 10-K, 20-F, 11-K or Form N-SAR, or portion thereof will be filed
[x]      on or  before  the  15th  calendar  day  following  the prescribed due
         date; or the subject quarterly report or transition report on Form
         10-Q, or portion thereof will be filed on or before the fifth calendar
         day following the prescribed due date; and

     (c) The  accountant's  statement  or other  exhibit  required by Rule
         12b-25(c) has been attached if applicable.

                                    PART III
                                    NARRATIVE

     State below in reasonable detail why the Form 10-K, 11-K, 20-F 10-Q, N-SAR
or the transition report portion thereof could not be filed within the
prescribed time period. (Attach extra sheets if needed.)

         The Registrant has experienced significant delays in preparing its Form
10-K for the period ended December 31, 2001, which could not have been avoided
without unreasonable effort or expense. As previously disclosed in a Current
Report on Form 8-K dated March 5, 2003, the Registrant completed a significant
merger transaction on February 21, 2003. In connection with this transaction,
there were significant changes in the Registrant's management, including the
appointment of a new president and chief executive officer and four new
directors. The merger transaction and subsequent transition period have caused
significant delays and increased effort in preparing the Registrant's Form
10-KSB for the year ended December 31, 2002. Accordingly, the Registrant is
unable to file the Form 10-KSB within the prescribed period without unreasonable
effort and expense.

                                     PART IV
                                OTHER INFORMATION

(1)  Name and telephone number of person to contact in regard to this
     notification

     Nicholas J. Rossettos                   (212) 554-4555
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        (Name)                          (Area Code) (Telephone Number)

(2)  Have all other periodic reports required under Section 13 or 15(d)of the
     Securities Exchange Act of 1934 or Section 30 of the Investment Company Act
     of 1940 during the preceding 12 months or for such shorter period that the
     registrant was required to file such report(s) been filed? If the answer is
     no, identify report(s).
                                                                  [x] Yes [ ] No




(3)  Is it anticipated that any significant change in results of operations from
     the corresponding period for the last fiscal year will be reflected by the
     earnings statements to be included in the subject report or portion
     thereof?
                                                                 [ ] Yes  [x] No

     If so: attach an explanation of the anticipated change, both narratively
and quantitatively, and, if appropriate, state the reasons why a reasonable
estimate of the results cannot be made.


                         Manhattan Pharmaceuticals, Inc.
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                  (Name of Registrant as Specified in Charter)

Has caused this notification to be signed on its behalf by the undersigned
thereunto duly authorized.


Date      March 31, 2003                By  /s/ Nicholas J. Rossettos
                                           ----------------------------------
                                           Nicholas J. Rossettos
                                           Its Chief Financial Officer

          INSTRUCTION: The form may be signed by an executive officer of the
     registrant or by any other duly authorized representative. The name and
     title of the person signing the form shall be typed or printed beneath the
     signature. If the statement is signed on behalf of the registrant by an
     authorized representative (other than an executive officer), evidence of
     the representative's authority to sign on behalf of the registrant shall be
     filed with the form.

                                    ATTENTION

     Intentional misstatements or omissions of fact constitute Federal Criminal
Violations (see 18 U.S.C. 1001).