DES MOINES, IOWA – EXCLUSIVE – Former Vice President Mike Pence takes aim at President Biden and the Democrats, takes a subtle jab at his one-time running mate – former President Donald Trump – and evokes the late President Ronald Reagan, as he announced his 2024 Republican presidential campaign in a launch video.

"President Joe Biden and the radical left have weakened America at home and abroad," Pence argues in his video, which was shared first with Fox News on Wednesday morning.

The video’s release came hours before the former vice president is expected to formally declare his candidacy in Iowa, the state whose caucuses lead off the GOP presidential nominating calendar.

"The American dream is being crushed under runaway inflation. Wages are dropping. Recession is looming. Our southern border is under siege and the enemies of freedom are on the march around the world. And worse still, timeless American values are under assault as never before," Pence charged.

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But portraying an optimistic vision for the future, Pence says "we can turn this country around. But different times call for different leadership. Today, our party and our country need a leader that will appeal, as Lincoln said, to the better angels of our nature."

"I have long believed to whom much is given, much will be required. My family and I have been blessed beyond measure with opportunities to serve this nation and it would be easy to stay on the sidelines. But that’s now how I was raised," Pence emphasized in his video before announcing that "that’s why today, before God and my family, I’m announcing I’m running for President of the United States."

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Pence is joining a growing field of Republican White House contenders that’s currently dominated by Trump – his one-time boss. Pence is the first running mate in eight decades to run against his former boss, since Vice President John Nance Garner unsuccessfully challenged President Franklin Roosevelt in the 1940 election.

Pence enters the 2024 race polling the mid-single digits, far behind Trump and also significantly trailing Florida Gov. Ron DeSantis, who trails Trump by double-digits but is firmly in second place, ahead of the former vice president and the rest of the field of actual and likely candidates.

Pence was Indiana governor when Trump named him his running mate in 2016. For four years, Pence served as the loyal vice president to Trump.

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However, everything changed on Jan. 6, 2021, as right-wing extremists — including some chanting "hang Mike Pence" — stormed the U.S. Capitol aiming to upend congressional certification of President Biden’s Electoral College victory that was overseen by Pence.

In the more than two years since the end of the Trump administration, the former president and vice president have drifted farther apart. Pence has rebuked his former boss, calling him out by name while discussing Trump's claim that Pence could have overturned the results of the 2020 presidential election.

When asked in recent months about Trump, Pence has reiterated that "I think that we’ll have better choices in 2024." And in his stump speeches, he touts the Trump-Pence administration’s policy successes but contrasts himself with the controversial former president in terms of tone and tenor.

"We can turn this country around. But different times call for different leadership. Today, our party and our country need a leader that will appeal, as Lincoln said, to the better angels of our nature," Pence said in his video, in an apparent swipe at Trump.

Looking ahead, Pence emphasized that "we can bring this country back. We can defend our nation and secure our border. We can revive our economy and put our nation back on a path to a balanced budget, defend our liberties and give America a new beginning for life."

He also twice in his video evoked Reagan, who remains a legend for conservatives. 

"President Reagan described us as a shining city on a hill. And above all, he called on Americans to renew optimism and believe in themselves again – to believe in each other," the former vice president said. "Every time our nation has produced leadership that has called on our country to do hard things, the American people have always risen to the challenge – and we will again. We just need government as good as our people to do it."

And Pence, who’s long been a champion for social conservatives and who’s expected to heavily court Iowa’s influential evangelical voters, stressed "I believe in the American people and I have faith – God is not done with America yet. And together we can bring this country back and the best days for the greatest nation on earth are yet to come. God bless you and God bless the United States of America." 

The son of Indiana also spotlighted his roots and his long career in public service, saying the "land of the free – home of the brave. The United States of America. As a son of the heartland, grandson of an Irish immigrant, those aren’t just words. My family has lived the American dream. I had the great honor to serve in Congress, as governor, and as your vice president. And I’ll always be proud of the progress we made together for a stronger, more prosperous America."